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SOD1-Derlin-1 inhibitor-1
CAS No. 840461-03-2
SOD1-Derlin-1 inhibitor-1( —— )
Catalog No. M35328 CAS No. 840461-03-2
SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | Get Quote |
|
| 10MG | 46 | Get Quote |
|
| 25MG | 90 | Get Quote |
|
| 50MG | 136 | Get Quote |
|
| 100MG | 201 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSOD1-Derlin-1 inhibitor-1
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NoteResearch use only, not for human use.
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Brief DescriptionSOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM.
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DescriptionSOD1-Derlin-1 inhibitor-1 (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for the research of amyotrophic lateral sclerosis.
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In VitroSOD1-Derlin-1 inhibitor-1 (50 μM; 16 h) inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 (250 nM; 6 h) interacts with SOD1G93A with a Kd value of 81.1 μM.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number840461-03-2
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Formula Weight504.2
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Molecular FormulaC19H12Br2N4OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 2.7 mg/mL (5.36 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C)
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SMILESNC=1C=2C(SC1C(NC3=C(Br)C=C(Br)C=C3)=O)=NC(=CC2)C=4C=CC=NC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tsuburaya N, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. Nat Commun. 2018 Jul 10;9(1):2668.?
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